Carbetocin Versus Oxytocin in Prevention of Atonic Postpartum Hemorrhage

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Misoprostol versus Oxytocin in Prevention of Postpartum Hemorrhage

Study background: The present study was done to compare oxytocin and misoprostol in active management of third stage of labor. Materials and methods: Total of 200 pregnant women were enrolled in the study were divided into two randomized groups. Group ‘A’ included 100 primigravidas with singleton pregnancy and normal vaginal delivery, who received 600μg misoprostol sublingually with delivery of...

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Prevention of postpartum haemorrhage with the oxytocin analogue carbetocin.

Postpartum haemorrhage is the leading cause of maternal mortality worldwide: 67-80% of cases are caused by uterine atony. Preventive measures include prophylactic drug use to aid uterine contraction after delivery, thus avoiding severe blood loss and reducing maternal morbidity and mortality. Carbetocin is a synthetic analogue of oxytocin with a half-life approximately 4-10 times longer than th...

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Adverse Effects of Carbetocin versus Oxytocin in the Prevention of Postpartum Haemorrhage after Caesarean Section: A Randomized Controlled Trial

Purpose To compare the incidence of nausea, vomiting, and arterial hypotension between carbetocin and oxytocin to prevent haemorrhage after caesarean section (CS). Methods A randomized controlled trial in term pregnant women undergoing planned CS. Groups were randomized to carbetocin or oxytocin. Blood pressure (BP), heart rate, presence of nausea/vomitus, and need for vasopressors were evalu...

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Carbetocin vs. Syntometrine in Prevention of Postpartum Hemorrhage: a Double Blind Randomized Control Trial

BACKGROUND Postpartum hemorrhage is a significant cause of maternal mortality and morbidity, worldwide. OBJECTIVES The aim of this study was to compare the efficacy between carbetocin and syntometrine in prevention of postpartum hemorrhage. MATERIALS AND METHODS This study was a double blind randomized clinical trial that carried out on 200 pregnant women referred to Shabiehkhani maternity c...

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Safety and Efficacy of Misoprostol versus Oxytocin for the Prevention of Postpartum Hemorrhage

Postpartum hemorrhage (PPH) is the commonest cause of maternal death worldwide. Studies suggest that the use of misoprostol may be beneficial in clinical settings where oxytocin is unavailable. The aim of this study was to compare the safety and efficacy of oxytocin and misoprostol when used in the prevention of PPH. In a double-blind randomized controlled trial, 400 pregnant women who had a va...

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ژورنال

عنوان ژورنال: The Egyptian Journal of Hospital Medicine

سال: 2019

ISSN: 2090-7125

DOI: 10.21608/ejhm.2019.48509